BACKGROUND: Septicemia constitutes a significant public health problem and it is an important cause of morbidity and mortality in hospitalized patients especially in children and neonates in developing countries, where identification of the germ and treatment is usually unsatisfactory. AIM: The aim of this study was to assess the prevalence of bacterial isolates and antimicrobial susceptibility patterns among septicemia suspected patients in the University teaching Hospital (UTH) Yaoundé. MATERIALS AND METHODS: This was a hospital based cross sectional study that was carried out for a period of 4 months among septicemia suspected hospitalized patients in the University Teaching Hospital (UTH) Yaoundé. Standard procedure was followed for blood sample collection, isolation, identifications and antimicrobial susceptibility testing. The data were analyzed by using EPI info and SPSS. RESULTS: Out of 255 blood culture results, 65 (25.5%) had septicemia. The predominant bacteria isolated from blood culture were Coagulase negative staphylococci 42 (64.6%), followed by Klebiesellaspp 8 (12.3%), E. coli 7(10.8%), Acinetobacterspp 4 (6.2%) and Streptococcus spp. 2 (3.1%) S. aureus 1 (1.5%) and Enterobacterspp 1 (1.5%). The Gram positive and Gram negative bacteria constituted 45(69.2%) and 20(30.8%) of the culture isolates respectively. Children between the ages of 0 -15 years constituted the greatest percentage of infected subjects (28.4%) (P >0.05). The highest incidence of septicemia were from pediatric ward 25 (30.9%) and neonatal ward 24 (26.1%). There was a significant association between septicemia and the body temperature of the patient (P?=?0.0272). Our finding, indicates that Gram negative bacteria exhibited a greater level of antimicrobial resistance (12.5%– 87.5%) than Gram positive bacteria (2.4% – 50%) to various antibacterial agents used in the study. CONCLUSION: The consequences of using an ineffective drug in severe bacterial infections could be disastrous as this can complicate management and increase morbidity and mortality
Septicemia, Antimicrobial Sensitivity, Cameroon, Blood Culture
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